Chemotherapy for gastric (stomach) cancer often involves a combination of drugs. These combinations are used to increase the effectiveness of treatment by attacking the cancer cells in different ways. Here are some common drug combinations used in the treatment of gastric cancer:
- ECF: includes Epirubicin, Cisplatin, and Fluorouracil (5-FU).
- ECX: includes Epirubicin, Cisplatin, and Capecitabine (an oral drug that is converted into 5-FU in the body).
- DCF: includes Docetaxel, Cisplatin, and Fluorouracil (5-FU).
- FOLFOX: includes Fluorouracil (5-FU), Leucovorin, and Oxaliplatin.
- Cisplatin and Capecitabine: a two-drug combination that’s sometimes used.
- Cisplatin and 5-FU: Another two-drug combination that’s sometimes used.
- Trastuzumab (Herceptin): This is a targeted therapy drug that’s used in combination with chemotherapy for stomach cancers that are HER2-positive.
The choice of chemotherapy regimen depends on several factors, including the type and stage of gastric cancer, the patient’s overall health, and the patient’s personal preferences. The potential benefits of each regimen must be weighed against the potential side effects. As always, these decisions should be made in consultation with a healthcare provider.